So, thyroid hormone for the win, right? What's not to love?

所以，激素是最棒的，对吗？还有啥理由不爱它呢。

As for fixing human hearts? Perhaps manipulating thyroid hormone levels could be a start.

那人类心脏能修复吗？也许可以从控制激素水平开始。

Or like you start off by explaining it, okay, hypothyroidism, okay, it's obviously where you produce less thyroid hormone.

或者你开始解释，好的，功能减退，显然是你产生的激素较少。

Because when they added extra thyroid hormone to zebrafish's tanks, their tiny hearts were no longer able to regenerate.

因为当他们向斑马鱼鱼缸中加入额外的激素时，斑马鱼的小心脏便不能再生了。

This results in growth of the thyroid glands and stimulates the follicular cells to produce excess thyroid hormone.

这会导致增生并刺激滤泡细胞，产生过量的激素。

Another primary cause is toxic nodular goiter where one or more follicles starts generating lots of thyroid hormone.

另一个原发病因是毒性结节性肿，即一个或多个滤泡开始产生大量的激素。

Also anytime the thyroid gets inflamed or damaged there can be a large release of preformed thyroid hormones.

发炎或受损，也可能大量释放预先形成的激素。

If there's too much thyroid hormone, they both decrease their own hormone production, to stop stimulating the thyroid.

如果激素过多，它们都会减少自身的激素分泌，停止刺激。

Like steroids, thyroid hormone is lipid-soluble, so it crosses the membrane of its target cell to bind inside the nucleus.

像类固醇一样，激素是脂溶性的，所以它穿过靶细胞的膜与细胞核结合。

Hassen called the lab. He ordered tests to check the level of thyroid hormone in the sample. It was very high.

哈森打电话给实验室，要求化验样本中激素的含量。结果显示激素含量非常高。

A medication called methimazole, for example, decreases production of thyroid hormones.

例如，一种叫做巯咪唑的药物会减少激素的产生。

If it's due to a primary cause, TSH will be low, an unbound thyroid hormones will be high.

如果是原发性亢，TSH水平将会很低，未结合的激素水平会变高。

Perhaps manipulating thyroid hormone levels could be a start.

或许操纵激素水平可能是一个开始。

That in turn reduces thyroid hormone levels in the blood, and slows down your metabolism again, before you get over-heated.

这反过来会降低血液中的激素水平，并在你过热之前再次减慢你的新陈代谢。

Rarely, in some people - usually young, often male - too much thyroid hormone can make circulating potassium levels drop and cause weakness.

激素过量会使循环钾含量下降，继而导致虚弱，这通常出现在年轻男性身上，但很罕见。

All of them result in too much thyroid hormone in a hyper metabolic state where cellular reactions are happening faster than normal.

其后果都是产生过多的激素，形成高代谢态，即细胞反应比正常情况发生得更快。

And hypo- and hyperthyroidism occur when the thyroid gland makes too little or too much thyroid hormone.

当产生的激素过少或过多时，就会发生功能减退症和功能亢进症。

Too much thyroid hormone causes the body to race. Too little, and it slows to a crawl. Unchecked, either state can be fatal.

激素过多会导致身体处于亢奋态。而激素过少，身体慢慢变得迟钝。如果放任不管，任何一种态都可能致命。

One example, is a struma ovarii tumor which is made up of only thyroid tissue and can release thyroid hormone which leads to hyperthyroidism.

其中一个例子是卵巢肿，只由组织组成，并且可以分泌素，造成亢。

And she was losing weight even though she was eating all the time, because the thyroid hormone was no longer regulating her metabolism properly.

即使她一直在吃东西，她的体重也在下降，因为激素不再正常调节她的新陈代谢。